Nanotechnological approaches for the development of novel antimicrobial strategies

Mohammed Dyia Hussien, Luminiţa Măruţescu, Carmen Mariana Chifiriuc      Published online: 15 June 2018

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Abstract Due to their diverse and multiple antimicrobial features, inorganic and organic nanoparticles (NPs) represent promising candidates for the development of novel antimicrobial strategies, which could be used to complement current antimicrobial agents that fail to combat pathogens, including multidrug-resistant and biofilm-forming microorganisms. The high surface / volume ratio of NPs provides a maximum loading of therapeutic molecules. Additionally, NPs coated with different antimicrobial agents could represent an important alternative strategy to combat biofilm infections. Among the most common types of NPs, the metal, metal oxide and carbon-based NPs are the most used for antimicrobial applications and the purpose of this review is to present some of their antimicrobial features.


Keywords nanoparticles, antimicrobial, anti-biofilm


Corresponding author: Luminiţa Măruţescu, E-mail: